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The mitochondrially targeted peptide elamipretide (SS-31) improves ADP sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide translocator (ANT).
Pharaoh, Gavin; Kamat, Varun; Kannan, Sricharan; Stuppard, Rudolph S; Whitson, Jeremy; Martín-Pérez, Miguel; Qian, Wei-Jun; MacCoss, Michael J; Villén, Judit; Rabinovitch, Peter; Campbell, Matthew D; Sweet, Ian R; Marcinek, David J.
Afiliação
  • Pharaoh G; Department of Radiology, University of Washington, Seattle, WA, 98195, USA.
  • Kamat V; Department of Medicine, University of Washington, Seattle, WA, 98195, USA.
  • Kannan S; Department of Radiology, University of Washington, Seattle, WA, 98195, USA.
  • Stuppard RS; Department of Radiology, University of Washington, Seattle, WA, 98195, USA.
  • Whitson J; Department of Biology, High Point University, High Point, NC, 27268, USA.
  • Martín-Pérez M; Department of Cell Biology, Physiology and Immunology, University of Barcelona, 08028, Barcelona, Spain.
  • Qian WJ; Integrative Omics Group, Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, 99352, USA.
  • MacCoss MJ; Department of Genome Sciences, University of Washington, Seattle, WA, 98195, USA.
  • Villén J; Department of Genome Sciences, University of Washington, Seattle, WA, 98195, USA.
  • Rabinovitch P; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, 98195, USA.
  • Campbell MD; Department of Radiology, University of Washington, Seattle, WA, 98195, USA.
  • Sweet IR; Department of Medicine, University of Washington, Seattle, WA, 98195, USA.
  • Marcinek DJ; Department of Radiology, University of Washington, Seattle, WA, 98195, USA. dmarc@uw.edu.
Geroscience ; 45(6): 3529-3548, 2023 Dec.
Article em En | MEDLINE | ID: mdl-37462785
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trifosfato de Adenosina / Mitocôndrias Tipo de estudo: Diagnostic_studies Idioma: En Revista: Geroscience Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trifosfato de Adenosina / Mitocôndrias Tipo de estudo: Diagnostic_studies Idioma: En Revista: Geroscience Ano de publicação: 2023 Tipo de documento: Article