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Recent Advances in the Biological Responses to Nano-black Phosphorus: Understanding the Importance of Intrinsic Properties and Cell Types.
Zhao, Qing; Donskyi, Ievgen S; Xiong, Zhiqiang; Liu, Daxu; Page, Taylor M; Zhang, Siyu; Deng, Shuo; Xu, Yuze; Zeng, Jin; Wu, Fengchang; Zhang, Xuejiao.
Afiliação
  • Zhao Q; National-Regional Joint Engineering Research Center for Soil Pollution Control and Remediation in South China, Guangdong Key Laboratory of Integrated Agro-environmental Pollution Control and Management, Institute of Eco-environmental and Soil Sciences, Guangdong Academy of Sciences, Guangzhou 510650
  • Donskyi IS; Key Laboratory of Pollution Ecology and Environmental Engineering, Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016, China.
  • Xiong Z; Institut für Chemie und Biochemie, Freie Universität Berlin, Takustrasse 3, 14195 Berlin, Germany.
  • Liu D; National-Regional Joint Engineering Research Center for Soil Pollution Control and Remediation in South China, Guangdong Key Laboratory of Integrated Agro-environmental Pollution Control and Management, Institute of Eco-environmental and Soil Sciences, Guangdong Academy of Sciences, Guangzhou 510650
  • Page TM; Key Laboratory of Pollution Ecology and Environmental Engineering, Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016, China.
  • Zhang S; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Deng S; Institut für Chemie und Biochemie, Freie Universität Berlin, Takustrasse 3, 14195 Berlin, Germany.
  • Xu Y; Key Laboratory of Pollution Ecology and Environmental Engineering, Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016, China.
  • Zeng J; Key Laboratory of Pollution Ecology and Environmental Engineering, Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016, China.
  • Wu F; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Zhang X; Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7.
Environ Sci Technol ; 57(31): 11373-11388, 2023 08 08.
Article em En | MEDLINE | ID: mdl-37470763
The production scalability and increasing demand for nano-black phosphorus materials (nano-BPs) inevitably lead to their environmental leakage, thereby raising the risk of human exposure through inhalation, ingestion, dermal, and even intravenous pathways. Consequently, a systematic evaluation of their potential impacts on human health is necessary. This Review outlines recent progress in the understanding of various biological responses to nano-BPs. Attention is particularly given to the inconsistent toxicological findings caused by a wide variation of nano-BPs' physicochemical properties, toxicological testing methods, and cell types examined in each study. Additionally, cellular uptake and intracellular trafficking, cell death modes, immunological effects, and other biologically relevant processes are discussed in detail, providing evidence for the potential health implications of nano-BPs. Finally, we address the remaining challenges related to the health risk evaluation of nano-BPs and propose a broader range of applications for these promising nanomaterials.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fósforo / Nanoestruturas Limite: Humans Idioma: En Revista: Environ Sci Technol Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fósforo / Nanoestruturas Limite: Humans Idioma: En Revista: Environ Sci Technol Ano de publicação: 2023 Tipo de documento: Article