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Thrombin cleavage of the hepatitis E virus polyprotein at multiple conserved locations is required for genome replication.
Pierce, Danielle M; Buchanan, Frazer J T; Macrae, Fraser L; Mills, Jake T; Cox, Abigail; Abualsaoud, Khadijah M; Ward, Joseph C; Ariëns, Robert A S; Harris, Mark; Stonehouse, Nicola J; Herod, Morgan R.
Afiliação
  • Pierce DM; School of Molecular and Cellular Biology, Faculty of Biological Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom.
  • Buchanan FJT; School of Molecular and Cellular Biology, Faculty of Biological Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom.
  • Macrae FL; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom.
  • Mills JT; School of Molecular and Cellular Biology, Faculty of Biological Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom.
  • Cox A; School of Molecular and Cellular Biology, Faculty of Biological Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom.
  • Abualsaoud KM; School of Molecular and Cellular Biology, Faculty of Biological Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom.
  • Ward JC; Department of Laboratory and Blood Bank, Al Mikhwah General Hospital, Al Mikhwah, Saudi Arabia.
  • Ariëns RAS; School of Molecular and Cellular Biology, Faculty of Biological Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom.
  • Harris M; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom.
  • Stonehouse NJ; School of Molecular and Cellular Biology, Faculty of Biological Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom.
  • Herod MR; School of Molecular and Cellular Biology, Faculty of Biological Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom.
PLoS Pathog ; 19(7): e1011529, 2023 07.
Article em En | MEDLINE | ID: mdl-37478143

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Hepatite E Idioma: En Revista: PLoS Pathog Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Hepatite E Idioma: En Revista: PLoS Pathog Ano de publicação: 2023 Tipo de documento: Article