Nailfold capillaroscopy findings of interstitial pneumonia with autoimmune features.
Korean J Intern Med
; 38(6): 903-911, 2023 11.
Article
em En
| MEDLINE
| ID: mdl-37488834
ABSTRACT
BACKGROUND/AIMS:
We evaluated nailfold capillaroscopy (NFC) of interstitial pneumonia with autoimmune features (IPAF) and compared it with that of patients with connective tissue disease-interstitial lung disease (CTD-ILD) and idiopathic interstitial pneumonia (IIP).METHODS:
Patients with newly diagnosed as ILD were evaluated using NFC. Baseline demographic, clinical, serological, and high-resolution CT findings were collected. NFC was semi-quantitatively scored with six domains ranging from 0 to 18. In addition, the overall patterns (scleroderma/non-scleroderma patterns) were determined.RESULTS:
A total of 81 patients (31 with CTD-ILD, 18 with IPAF, and 32 with IIP) were included. The non-specific interstitial pneumonia pattern was the most common ILD pattern in the CTD-ILD and IPAF groups, whereas the usual interstitial pneumonia pattern was the most common in the IIP group. The semi-quantitative score of the CTD-ILD group was higher than that of the IPAF or IIP groups (5.8 vs 4.2 vs 3.0, p < 0.001, respectively). Giant capillaries and haemorrhages were more frequently present in the CTD-ILD and IPAF groups than in the IIP group. A scleroderma pattern was present in 27.8% of the IPAF group, whereas none of the IIP patients showed a scleroderma pattern.CONCLUSION:
NFC findings may be useful in classifying patients with ILD into CTD-ILD/IPAF/IIP.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças Pulmonares Intersticiais
/
Doenças do Tecido Conjuntivo
/
Pneumonias Intersticiais Idiopáticas
/
Fibrose Pulmonar Idiopática
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Korean J Intern Med
Ano de publicação:
2023
Tipo de documento:
Article