Sertindole, an Antipsychotic Drug, Curbs the STAT3/BCL-xL Axis to Elicit Human Bladder Cancer Cell Apoptosis In Vitro.

Hsu, Chao-Yu; Yang, Wei-Ting; Lin, Ju-Hwa; Lu, Chien-Hsing; Hu, Kai-Cheng; Lan, Tsuo-Hung; Chang, Chia-Che

Hsu, Chao-Yu; Yang, Wei-Ting; Lin, Ju-Hwa; Lu, Chien-Hsing; Hu, Kai-Cheng; Lan, Tsuo-Hung; Chang, Chia-Che.

Afiliação

Hsu CY; Division of Urology, Department of Surgery, Tungs' Taichung MetroHarbor Hospital, Taichung 435403, Taiwan.
Yang WT; Doctoral Program in Translational Medicine, National Chung Hsing University, Taichung 402202, Taiwan.
Lin JH; Department of Life Sciences, National Chung Hsing University, Taichung 402202, Taiwan.
Lu CH; Department of Biological Science and Technology, China Medical University, Taichung 406040, Taiwan.
Hu KC; Doctoral Program in Translational Medicine, National Chung Hsing University, Taichung 402202, Taiwan.
Lan TH; Department of Obstetrics and Gynecology, Taichung Veterans General Hospital, Taichung 407219, Taiwan.
Chang CC; Department of Life Sciences, National Chung Hsing University, Taichung 402202, Taiwan.

Int J Mol Sci ; 24(14)2023 Jul 24.

Article em En | MEDLINE | ID: mdl-37511611

Assuntos

Antipsicóticos; Neoplasias da Bexiga Urinária; Humanos; Antipsicóticos/farmacologia; Antipsicóticos/uso terapêutico; Fator de Transcrição STAT3/metabolismo; Apoptose; Neoplasias da Bexiga Urinária/tratamento farmacológico; Neoplasias da Bexiga Urinária/metabolismo; Proteína bcl-X/genética; Proteína bcl-X/metabolismo; Linhagem Celular Tumoral

Palavras-chave

BCL-xL; STAT3; antipsychotics; apoptosis; bladder cancer; sertindole

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antipsicóticos / Neoplasias da Bexiga Urinária Limite: Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2023 Tipo de documento: Article

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