Fragment Screening and Fast Micromolar Detection on a Benchtop NMR Spectrometer Boosted by Photoinduced Hyperpolarization.

Stadler, Gabriela R; Segawa, Takuya F; Bütikofer, Matthias; Decker, Venita; Loss, Sandra; Czarniecki, Barbara; Torres, Felix; Riek, Roland

Stadler, Gabriela R; Segawa, Takuya F; Bütikofer, Matthias; Decker, Venita; Loss, Sandra; Czarniecki, Barbara; Torres, Felix; Riek, Roland.

Afiliação

Stadler GR; ETH Zürich, Swiss Federal Institute of Technology, Institute for Molecular Physical Science, Vladimir-Prelog-Weg 2, 8093, Zürich, Switzerland.
Segawa TF; ETH Zürich, Swiss Federal Institute of Technology, Laboratory of Physical Chemistry, Vladimir-Prelog-Weg 2, 8093, Zürich, Switzerland.
Bütikofer M; ETH Zürich, Swiss Federal Institute of Technology, Institute for Molecular Physical Science, Vladimir-Prelog-Weg 2, 8093, Zürich, Switzerland.
Decker V; Bruker BioSpin GmbH, Rudolf-Plank-Strasse 23, 76275, Ettlingen, Germany.
Loss S; Bruker Switzerland AG, Industriestrasse 26, 8117, Fällanden, Switzerland.
Czarniecki B; Bruker Switzerland AG, Industriestrasse 26, 8117, Fällanden, Switzerland.
Torres F; ETH Zürich, Swiss Federal Institute of Technology, Institute for Molecular Physical Science, Vladimir-Prelog-Weg 2, 8093, Zürich, Switzerland.
Riek R; NexMR GmbH, Wiesenstrasse 10âA, 8952, Schlieren, Switzerland.

Angew Chem Int Ed Engl ; 62(40): e202308692, 2023 Oct 02.

Article em En | MEDLINE | ID: mdl-37524651

Palavras-chave

Drug Design; Fragment Screening; Fragment-Based Drug Design; Nuclear Magnetic Resonance; Photo-CIDNP

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Screening_studies Idioma: En Revista: Angew Chem Int Ed Engl Ano de publicação: 2023 Tipo de documento: Article

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