N-of-1 trials: The epitome of personalized medicine?
J Clin Transl Sci
; 7(1): e161, 2023.
Article
em En
| MEDLINE
| ID: mdl-37528940
ABSTRACT
Observational studies are notoriously susceptible to bias, and parallel-group randomized trials are important to identify the best overall treatment for eligible patients. Yet, such trials can be expected to be a misleading indicator of the best treatment for some subgroups or individual patients. In selected circumstances, patients can be treated in n-of-1 trials to address the inherent heterogeneity of treatment response in clinical populations. Such trials help to accomplish the ultimate goal of all biomedical research, to optimize the care of individual patients.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Clinical_trials
/
Observational_studies
Idioma:
En
Revista:
J Clin Transl Sci
Ano de publicação:
2023
Tipo de documento:
Article