Manganese-Based Immunostimulatory Metal-Organic Framework Activates the cGAS-STING Pathway for Cancer Metalloimmunotherapy.

Zheng, Sui-Juan; Yang, Mingfang; Luo, Jia-Qi; Liu, Rong; Song, Jie; Chen, Yao; Du, Jin-Zhi

Zheng, Sui-Juan; Yang, Mingfang; Luo, Jia-Qi; Liu, Rong; Song, Jie; Chen, Yao; Du, Jin-Zhi.

Afiliação

Zheng SJ; School of Medicine, South China University of Technology, Guangzhou 510006, China.
Yang M; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin 300071, China.
Luo JQ; School of Medicine, South China University of Technology, Guangzhou 510006, China.
Liu R; School of Medicine, South China University of Technology, Guangzhou 510006, China.
Song J; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin 300071, China.
Chen Y; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin 300071, China.
Du JZ; School of Medicine, South China University of Technology, Guangzhou 510006, China.

ACS Nano ; 17(16): 15905-15917, 2023 08 22.

Article em En | MEDLINE | ID: mdl-37565626

Assuntos

Estruturas Metalorgânicas; Neoplasias; Camundongos; Animais; Estruturas Metalorgânicas/farmacologia; Manganês/farmacologia; Proteínas de Membrana/metabolismo; Nucleotidiltransferases/metabolismo; Neoplasias/tratamento farmacológico

Palavras-chave

Cancer metalloimmunotherapy; Immunostimulatory nanomaterials; Manganese ions; Metal−organic frameworks; STING activation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estruturas Metalorgânicas / Neoplasias Limite: Animals Idioma: En Revista: ACS Nano Ano de publicação: 2023 Tipo de documento: Article

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