Analysis of the Analgesic Effect, Emotion, and Safety of Esketamine in Cesarean Section Analgesia for Puerperae.
Altern Ther Health Med
; 29(7): 424-428, 2023 Oct.
Article
em En
| MEDLINE
| ID: mdl-37573591
ABSTRACT
Objective:
This retrospective study aimed to evaluate the effectiveness and safety of esketamine as an analgesic during cesarean section procedures.Methods:
102 puerperae undergoing cesarean section were divided into a control group and an esketamine (SK) group. Various parameters, including HR, MAP, and postoperative pain, were analyzed. Blood gas analysis and Apgar scores were assessed in neonates. Postoperative depression and satisfaction were evaluated in puerperae. Drug concentrations were measured using liquid-phase tandem mass spectrometry.Results:
No significant differences in dimension levels were observed between the two groups (P > .05). However, the SK group showed better HR and MAP indicators at various time points, less postoperative pain, and better mental well-being on postpartum days 1, 3, and 7 (P < .05). Adverse reaction rates were similar between groups (P > .05), but postoperative satisfaction was significantly different (P = .027). Neonatal outcomes did not differ significantly (P > .05). In the SK group, SK2 and SK3 groups had better results compared to SK1 (P < .05).Conclusion:
Esketamine during cesarean section stabilized vital signs, reduced pain, and improved well-being in puerperae without affecting newborns. Optimal dosage 30 µg/kg/h esketamine, 15 ng/kg/h sufentanil.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cesárea
/
Analgesia
Tipo de estudo:
Observational_studies
Limite:
Female
/
Humans
/
Newborn
/
Pregnancy
Idioma:
En
Revista:
Altern Ther Health Med
Ano de publicação:
2023
Tipo de documento:
Article