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Development and validation of a hybrid immunoaffinity LC-MS/MS assay for quantitation of total antibody (TAb) from an antibody drug conjugate (ADC) PYX-201 in human plasma.
Yin, Feng; Adhikari, Diana; Peay, Marlking; Cortes, Diego; Garada, Mohammed; Shane Woolf, M; Ma, Eric; Lebarbenchon, Diane; Mylott, William; Dyszel, Mike; Harriman, Shawn; Pinkas, Jan.
Afiliação
  • Yin F; Department of Nonclinical Research, Pyxis Oncology, Inc, 321 Harrison Avenue, Suite 1, Boston, MA 02118, USA.
  • Adhikari D; Department of Nonclinical Research, Pyxis Oncology, Inc, 321 Harrison Avenue, Suite 1, Boston, MA 02118, USA.
  • Peay M; Chromatographic Services - Research & Development, Biologics by LC-MS/MS, PPD Laboratory Services (a part of ThermoFisher Scientific), 8700 Quioccasin Road, Henrico, VA 23229, USA.
  • Cortes D; Chromatographic Services - Research & Development, Biologics by LC-MS/MS, PPD Laboratory Services (a part of ThermoFisher Scientific), 8700 Quioccasin Road, Henrico, VA 23229, USA.
  • Garada M; Chromatographic Services - Research & Development, Biologics by LC-MS/MS, PPD Laboratory Services (a part of ThermoFisher Scientific), 8700 Quioccasin Road, Henrico, VA 23229, USA.
  • Shane Woolf M; Chromatographic Services - Research & Development, Biologics by LC-MS/MS, PPD Laboratory Services (a part of ThermoFisher Scientific), 8700 Quioccasin Road, Henrico, VA 23229, USA.
  • Ma E; Chromatographic Services - Research & Development, Biologics by LC-MS/MS, PPD Laboratory Services (a part of ThermoFisher Scientific), 8700 Quioccasin Road, Henrico, VA 23229, USA.
  • Lebarbenchon D; Chromatographic Services - Research & Development, Biologics by LC-MS/MS, PPD Laboratory Services (a part of ThermoFisher Scientific), 8700 Quioccasin Road, Henrico, VA 23229, USA.
  • Mylott W; Chromatographic Services - Research & Development, Biologics by LC-MS/MS, PPD Laboratory Services (a part of ThermoFisher Scientific), 8700 Quioccasin Road, Henrico, VA 23229, USA.
  • Dyszel M; Department of Project Management, Pyxis Oncology, Inc, 321 Harrison Avenue, Suite 1, Boston, MA 02118, USA.
  • Harriman S; Department of Nonclinical Research, Pyxis Oncology, Inc, 321 Harrison Avenue, Suite 1, Boston, MA 02118, USA. Electronic address: sharriman@pyxisoncology.com.
  • Pinkas J; Department of Nonclinical Research, Pyxis Oncology, Inc, 321 Harrison Avenue, Suite 1, Boston, MA 02118, USA. Electronic address: jpinkas@pyxisoncology.com.
J Chromatogr B Analyt Technol Biomed Life Sci ; 1228: 123844, 2023 Aug 01.
Article em En | MEDLINE | ID: mdl-37579604
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Espectrometria de Massas em Tandem Limite: Humans Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Espectrometria de Massas em Tandem Limite: Humans Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Ano de publicação: 2023 Tipo de documento: Article