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An in vitro assay to investigate venom neurotoxin activity on muscle-type nicotinic acetylcholine receptor activation and for the discovery of toxin-inhibitory molecules.
Patel, Rohit N; Clare, Rachel H; Ledsgaard, Line; Nys, Mieke; Kool, Jeroen; Laustsen, Andreas H; Ulens, Chris; Casewell, Nicholas R.
Afiliação
  • Patel RN; Centre for Snakebite Research & Interventions, Liverpool School of Tropical Medicine, L3 5QA, UK; Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, L3 5QA, UK.
  • Clare RH; Centre for Snakebite Research & Interventions, Liverpool School of Tropical Medicine, L3 5QA, UK; Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, L3 5QA, UK.
  • Ledsgaard L; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.
  • Nys M; Laboratory of Structural Neurobiology, Department of Cellular and Molecular Medicine, Faculty of Medicine, KU Leuven, Belgium.
  • Kool J; AIMMS Division of BioAnalytical Chemistry, Vrije Universiteit Amsterdam, Netherlands.
  • Laustsen AH; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.
  • Ulens C; Laboratory of Structural Neurobiology, Department of Cellular and Molecular Medicine, Faculty of Medicine, KU Leuven, Belgium.
  • Casewell NR; Centre for Snakebite Research & Interventions, Liverpool School of Tropical Medicine, L3 5QA, UK; Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, L3 5QA, UK. Electronic address: Nicholas.Casewell@lstmed.ac.uk.
Biochem Pharmacol ; 216: 115758, 2023 Oct.
Article em En | MEDLINE | ID: mdl-37604290
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Mordeduras de Serpentes / Receptores Nicotínicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Biochem Pharmacol Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Mordeduras de Serpentes / Receptores Nicotínicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Biochem Pharmacol Ano de publicação: 2023 Tipo de documento: Article