The A328 V/E (rs2887147) polymorphisms in human tryptophan hydroxylase 2 compromise enzyme activity.

Carkaci-Salli, Nurgul; Bewley, Maria C; Tekin, Izel; Flanagan, John M; Vrana, Kent E

The A328 V/E (rs2887147) polymorphisms in human tryptophan hydroxylase 2 compromise enzyme activity.

Carkaci-Salli, Nurgul; Bewley, Maria C; Tekin, Izel; Flanagan, John M; Vrana, Kent E.

Afiliação

Carkaci-Salli N; Departments of Pharmacology, Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA.
Bewley MC; Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA.
Tekin I; Departments of Pharmacology, Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA.
Flanagan JM; Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA.
Vrana KE; Departments of Pharmacology, Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA.

Biochem Biophys Rep ; 35: 101527, 2023 Sep.

Article em En | MEDLINE | ID: mdl-37608910

Palavras-chave

5-HT); Enzyme activity; Serotonin (5-hydroxytryptamine; Single nucleotide polymorphism; Substrate inhibition; Tryptophan hydroxylase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Biochem Biophys Rep Ano de publicação: 2023 Tipo de documento: Article

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