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Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser.
Kim, Hoyoung; Lim, Taehyun; Ha, Go Eun; Lee, Jee-Young; Kim, Jun-Woo; Chang, Nienping; Kim, Si Hyun; Kim, Ki Hun; Lee, Jaeick; Cho, Yongju; Kim, Byeong Wook; Abrahamsson, Alva; Kim, Sung Hwan; Kim, Hyo-Ji; Park, Sehan; Lee, Sang Jae; Park, Jaehyun; Cheong, Eunji; Kim, B Moon; Cho, Hyun-Soo.
Afiliação
  • Kim H; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, 50 Yonsei-ro, Seoul, 03722, Republic of Korea.
  • Lim T; Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul, 08826, Republic of Korea.
  • Ha GE; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea.
  • Lee JY; New Drug Development Center (NDDC), Daegu Gyeongbuk Medical Innovation Foundation (K-Medi hub), 80 Chumbok-ro, Dong-gu, Daegu, 41061, Korea.
  • Kim JW; New Drug Development Center (NDDC), Daegu Gyeongbuk Medical Innovation Foundation (K-Medi hub), 80 Chumbok-ro, Dong-gu, Daegu, 41061, Korea.
  • Chang N; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, 50 Yonsei-ro, Seoul, 03722, Republic of Korea.
  • Kim SH; Doping Control Center, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea.
  • Kim KH; Department of Chemistry, Sogang University, Seoul, 04107, Republic of Korea.
  • Lee J; Doping Control Center, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea.
  • Cho Y; Doping Control Center, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea.
  • Kim BW; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, 50 Yonsei-ro, Seoul, 03722, Republic of Korea.
  • Abrahamsson A; Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul, 08826, Republic of Korea.
  • Kim SH; Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul, 08826, Republic of Korea.
  • Kim HJ; New Drug Development Center (NDDC), Daegu Gyeongbuk Medical Innovation Foundation (K-Medi hub), 80 Chumbok-ro, Dong-gu, Daegu, 41061, Korea.
  • Park S; New Drug Development Center (NDDC), Daegu Gyeongbuk Medical Innovation Foundation (K-Medi hub), 80 Chumbok-ro, Dong-gu, Daegu, 41061, Korea.
  • Lee SJ; Pohang Accelerator Laboratory, POSTECH, Pohang, 37673, Republic of Korea.
  • Park J; Pohang Accelerator Laboratory, POSTECH, Pohang, 37673, Republic of Korea.
  • Cheong E; Pohang Accelerator Laboratory, POSTECH, Pohang, 37673, Republic of Korea.
  • Kim BM; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea. eunjicheong@yonsei.ac.kr.
  • Cho HS; Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul, 08826, Republic of Korea. kimbm@snu.ac.kr.
Exp Mol Med ; 55(9): 2039-2050, 2023 09.
Article em En | MEDLINE | ID: mdl-37653040
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Assunto principal: Hormônio Liberador da Corticotropina / Elétrons Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Exp Mol Med Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Assunto principal: Hormônio Liberador da Corticotropina / Elétrons Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Exp Mol Med Ano de publicação: 2023 Tipo de documento: Article