Carcinoid syndrome-Symptoms and therapeutic approaches.

ABSTRACT

The carcinoid syndrome (CS) is a constellation of symptoms attributed to hypersecretion of amines, prostaglandins and polypeptides. The cardinal symptoms of CS are flushing, diarrhea and bronchospasm; however, CS may present with various symptoms and signs, as Skin cutaneous flushes, cyanosis, pellagra, Gastrointestinal diarrhea, nausea, abdominal cramps, vomiting, Heart tricuspid and pulmonic valve thickening causing right heart failure, edema, Respiratory wheezing, dyspnea.