Discovery and Characterization of an Acid-Labile Serine-Lysine Cross-Link in Antibody High-Molecular-Weight Species Using a Multipronged Mass Spectrometry Approach.

Liu, Gao-Yuan; Zhang, Zhengqi; Yan, Yuetian; Wang, Shunhai; Li, Ning

Liu, Gao-Yuan; Zhang, Zhengqi; Yan, Yuetian; Wang, Shunhai; Li, Ning.

Afiliação

Liu GY; Analytical Chemistry, Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, New York 10591-6707, United States.
Zhang Z; Analytical Chemistry, Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, New York 10591-6707, United States.
Yan Y; Analytical Chemistry, Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, New York 10591-6707, United States.
Wang S; Analytical Chemistry, Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, New York 10591-6707, United States.
Li N; Analytical Chemistry, Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, New York 10591-6707, United States.

Anal Chem ; 95(37): 13813-13821, 2023 09 19.

Article em En | MEDLINE | ID: mdl-37674418

Assuntos

Anticorpos Monoclonais; Lisina; Iminas; Espectrometria de Massas; Serina

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lisina / Anticorpos Monoclonais Tipo de estudo: Risk_factors_studies Idioma: En Revista: Anal Chem Ano de publicação: 2023 Tipo de documento: Article

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