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Let the Guard Down: cAMP Activators Can Improve Immunotherapy in GBM.
Lee, Juyeun; Kay, Kristen E; Vogelbaum, Michael A; Lathia, Justin D.
Afiliação
  • Lee J; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.
  • Kay KE; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.
  • Vogelbaum MA; Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio.
  • Lathia JD; Department of NeuroOncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
Cancer Immunol Res ; 11(10): 1300-1301, 2023 10 04.
Article em En | MEDLINE | ID: mdl-37702792
ABSTRACT
Enhancing T-cell infiltration into glioblastoma (GBM) tumors has proven challenging yet remains crucial for improving the efficacy of immunotherapy for patients with this deadly cancer. In this issue, Qin, Huang, Li, and colleagues find that inhibiting vasculature formation driven by cancer stem cells is a promising target to enhance immunotherapy in GBM. See related article by Qin, Huang, Li, et al., p. 1351 (2).
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Glioblastoma Limite: Humans Idioma: En Revista: Cancer Immunol Res Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Glioblastoma Limite: Humans Idioma: En Revista: Cancer Immunol Res Ano de publicação: 2023 Tipo de documento: Article