Overall signature of acquired KRAS gene changes in advanced non-small cell lung cancer patient with EGFR-TKI resistance.

Zheng, Jie; Dou, Yuanyao; Huang, Daijuan; Wang, Yubo; Han, Rui; Hu, Chen; Zhu, Mengxiao; Lu, Conghua; Lin, Caiyu; Wu, Di; Liu, Yihui; Tang, Huan; He, Tingting; Jiang, Weilin; He, Yong

Zheng, Jie; Dou, Yuanyao; Huang, Daijuan; Wang, Yubo; Han, Rui; Hu, Chen; Zhu, Mengxiao; Lu, Conghua; Lin, Caiyu; Wu, Di; Liu, Yihui; Tang, Huan; He, Tingting; Jiang, Weilin; He, Yong.

Afiliação

Zheng J; School of Medicine, Chongqing University, Chongqing, China.
Dou Y; Department of Respiratory Disease, Daping Hospital, Army Medical University, Chongqing, China.
Huang D; Department of Respiratory Disease, Daping Hospital, Army Medical University, Chongqing, China.
Wang Y; Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, China.
Han R; School of Medicine, Chongqing University, Chongqing, China.
Hu C; Department of Respiratory Disease, Daping Hospital, Army Medical University, Chongqing, China.
Zhu M; Department of Respiratory Disease, Daping Hospital, Army Medical University, Chongqing, China.
Lu C; Department of Respiratory Disease, Daping Hospital, Army Medical University, Chongqing, China.
Lin C; Department of Respiratory Disease, Daping Hospital, Army Medical University, Chongqing, China.
Wu D; Department of Respiratory Disease, Daping Hospital, Army Medical University, Chongqing, China.
Liu Y; Department of Respiratory Disease, Daping Hospital, Army Medical University, Chongqing, China.
Tang H; Department of Respiratory Disease, Daping Hospital, Army Medical University, Chongqing, China.
He T; Department of Respiratory Disease, Daping Hospital, Army Medical University, Chongqing, China.
Jiang W; Department of Respiratory Disease, Daping Hospital, Army Medical University, Chongqing, China.
He Y; Department of Respiratory Disease, Daping Hospital, Army Medical University, Chongqing, China.

Jpn J Clin Oncol ; 54(1): 89-96, 2024 Jan 07.

Article em En | MEDLINE | ID: mdl-37721193

Assuntos

Carcinoma Pulmonar de Células não Pequenas; Neoplasias Pulmonares; Humanos; Carcinoma Pulmonar de Células não Pequenas/tratamento farmacológico; Carcinoma Pulmonar de Células não Pequenas/genética; Carcinoma Pulmonar de Células não Pequenas/patologia; Neoplasias Pulmonares/tratamento farmacológico; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/patologia; Proteínas Proto-Oncogênicas p21(ras)/genética; Estudos Retrospectivos; Inibidores de Proteínas Quinases/uso terapêutico; Inibidores de Proteínas Quinases/farmacologia; Quinazolinas; Receptores ErbB/genética; Mutação; Resistencia a Medicamentos Antineoplásicos/genética

Palavras-chave

EGFR-TKI resistance; KRAS 117N; KRAS G13D; KRAS gene fusion; acquired KRAS alterations; non-small cell lung cancer

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Jpn J Clin Oncol Ano de publicação: 2024 Tipo de documento: Article

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