Free Bilirubin Induces Neuro-Inflammation in an Induced Pluripotent Stem Cell-Derived Cortical Organoid Model of Crigler-Najjar Syndrome.

Pranty, Abida Islam; Wruck, Wasco; Adjaye, James

Pranty, Abida Islam; Wruck, Wasco; Adjaye, James.

Afiliação

Pranty AI; Institute for Stem Cell Research and Regenerative Medicine, Medical Faculty, Heinrich-Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Wruck W; Institute for Stem Cell Research and Regenerative Medicine, Medical Faculty, Heinrich-Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Adjaye J; Institute for Stem Cell Research and Regenerative Medicine, Medical Faculty, Heinrich-Heine University Düsseldorf, 40225 Düsseldorf, Germany.

Cells ; 12(18)2023 09 14.

Article em En | MEDLINE | ID: mdl-37759499

Assuntos

Síndrome de Crigler-Najjar; Células-Tronco Pluripotentes Induzidas; Kernicterus; Humanos; Encéfalo; Citocinas; Bilirrubina

Palavras-chave

3D brain organoid; BIND; CriglerNajjar syndrome; UGT1A1; free bilirubin; kernicterus; neuro-inflammation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome de Crigler-Najjar / Células-Tronco Pluripotentes Induzidas / Kernicterus Limite: Humans Idioma: En Revista: Cells Ano de publicação: 2023 Tipo de documento: Article

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