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Alpha-Linolenic Acid and Cardiovascular Events: A Narrative Review.
Bertoni, Camilla; Abodi, Martina; D'Oria, Veronica; Milani, Gregorio P; Agostoni, Carlo; Mazzocchi, Alessandra.
Afiliação
  • Bertoni C; Department of Veterinary Sciences for Health, Animal Production and Food Safety, University of Milan, 20122 Milan, Italy.
  • Abodi M; Department of Veterinary Sciences for Health, Animal Production and Food Safety, University of Milan, 20122 Milan, Italy.
  • D'Oria V; Pediatric Area, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
  • Milani GP; Pediatric Area, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
  • Agostoni C; Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.
  • Mazzocchi A; Pediatric Area, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Int J Mol Sci ; 24(18)2023 Sep 20.
Article em En | MEDLINE | ID: mdl-37762621
Cardiovascular diseases (CVDs) represent the leading cause of global mortality with 1.7 million deaths a year. One of the alternative systems to drug therapy to minimize the risk of CVDs is represented by alpha-linolenic acid (ALA), an essential fatty acid of the omega-3 series, known for its cholesterol-lowering effect. The main purpose of this review is to analyze the effects of ALA and investigate the relevant omega-6/omega-3 ratio in order to maintain functionally beneficial effects. Concerning the lipid-lowering preventive effects, ALA may favorably affect the values of LDL-C and triglycerides in both adult and pediatric populations. Furthermore, ALA has shown protective effects against hypertension, contributing to balancing blood pressure through customary diet. According to the 2009 EFSA statement, dietary ALA may contribute to reducing the risk of CVDs, thanks to anti-hypertensive, anti-atherosclerotic and cardioprotective effects.
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 / 2_ODS3 / 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Doenças Cardiovasculares / Ácidos Graxos Ômega-3 / Hipertensão Limite: Adult / Child / Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 / 2_ODS3 / 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Doenças Cardiovasculares / Ácidos Graxos Ômega-3 / Hipertensão Limite: Adult / Child / Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2023 Tipo de documento: Article