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Nebulized Recombinant Tissue Plasminogen Activator (rt-PA) for Acute COVID-19-Induced Respiratory Failure: An Exploratory Proof-of-Concept Trial.
Chowdary, Pratima; Agarwal, Banwari; Peralta, Maria Rita; Bhagani, Sanjay; Lee, Simon; Goldring, James; Lipman, Marc; Waqif, Emal; Phillips, Mark; Philippou, Helen; Foley, Jonathan H; Mutch, Nicola J; Ariëns, Robert A S; Stringer, Kathleen A; Ricciardi, Federico; Watissée, Marie; Hughes, Derralynn; Nathwani, Amit; Riddell, Anne; Patch, David; Buckley, Jim; De Neef, Mark; Dimber, Rahul; Diaz-Garcia, Cecilia; Patel, Honey; Nandani, Aarti; Dissanayake, Upuli; Chadwick, Nick; Alkhatip, Ahmed A A M M; Watkinson, Peter; Raith, Eamon; Singh, Suveer; Wolff, Tony; Jha, Rajeev; Brill, Simon E; Bakhai, Ameet; Evans, Alison; Gilani, Farhat; Gomez, Keith.
Afiliação
  • Chowdary P; Katharine Dormandy Haemophilia and Thrombosis Centre, Royal Free London NHS Foundation Trust, London NW3 2QG, UK.
  • Agarwal B; Cancer Institute, University College London, London WC1E 6DD, UK.
  • Peralta MR; Department of Intensive Care and Anaesthesia, Royal Free London NHS Foundation Trust, London NW3 2QG, UK.
  • Bhagani S; Katharine Dormandy Haemophilia and Thrombosis Centre, Royal Free London NHS Foundation Trust, London NW3 2QG, UK.
  • Lee S; Cancer Institute, University College London, London WC1E 6DD, UK.
  • Goldring J; Department of Infectious Diseases, Royal Free London NHS Foundation Trust, London NW3 2QG, UK.
  • Lipman M; Department of Infectious Diseases, Royal Free London NHS Foundation Trust, London NW3 2QG, UK.
  • Waqif E; Respiratory Medicine, Royal Free London NHS Foundation Trust, London NW1 2BU, UK.
  • Phillips M; Respiratory Medicine, Royal Free London NHS Foundation Trust, London NW1 2BU, UK.
  • Philippou H; UCL Respiratory, University College London, London WC1E 6JF, UK.
  • Foley JH; Katharine Dormandy Haemophilia and Thrombosis Centre, Royal Free London NHS Foundation Trust, London NW3 2QG, UK.
  • Mutch NJ; Katharine Dormandy Haemophilia and Thrombosis Centre, Royal Free London NHS Foundation Trust, London NW3 2QG, UK.
  • Ariëns RAS; Cancer Institute, University College London, London WC1E 6DD, UK.
  • Stringer KA; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds LS2 9JT, UK.
  • Ricciardi F; Freeline Therapeutics, London SG1 2BP, UK.
  • Watissée M; Aberdeen Cardiovascular & Diabetes Centre, School of Medicine, Medical Sciences & Nutrition, Institute of Medical Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK.
  • Hughes D; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds LS2 9JT, UK.
  • Nathwani A; Department of Clinical Pharmacy, College of Pharmacy University of Michigan, Ann Arbor, MI 48109, USA.
  • Riddell A; Division of Pulmonary and Critical Care Medicine, School of Medicine, University of Michigan, Ann Arbor, MI 48109, USA.
  • Patch D; Department of Statistical Science, University College London, London WC1E 6BT, UK.
  • Buckley J; WStats Limited, Winchester SO23 8GH, UK.
  • De Neef M; Cancer Institute, University College London, London WC1E 6DD, UK.
  • Dimber R; Katharine Dormandy Haemophilia and Thrombosis Centre, Royal Free London NHS Foundation Trust, London NW3 2QG, UK.
  • Diaz-Garcia C; Cancer Institute, University College London, London WC1E 6DD, UK.
  • Patel H; Katharine Dormandy Haemophilia and Thrombosis Centre, Royal Free London NHS Foundation Trust, London NW3 2QG, UK.
  • Nandani A; Haemophilia & Thrombosis Laboratory (Health Services Laboratories), Royal Free Hospital, London WC1H 9AX, UK.
  • Dissanayake U; Department of Hepatology, Royal Free London NHS Foundation Trust, London NW3 2QG, UK.
  • Chadwick N; Department of Intensive Care and Anaesthesia, Royal Free London NHS Foundation Trust, London NW3 2QG, UK.
  • Alkhatip AAAMM; Department of Intensive Care and Anaesthesia, Royal Free London NHS Foundation Trust, London NW3 2QG, UK.
  • Watkinson P; Department of Intensive Care and Anaesthesia, Royal Free London NHS Foundation Trust, London NW3 2QG, UK.
  • Raith E; Katharine Dormandy Haemophilia and Thrombosis Centre, Royal Free London NHS Foundation Trust, London NW3 2QG, UK.
  • Singh S; Katharine Dormandy Haemophilia and Thrombosis Centre, Royal Free London NHS Foundation Trust, London NW3 2QG, UK.
  • Wolff T; Clinical Trials Pharmacy, Royal Free London NHS Foundation Trust, London NW3 2QG, UK.
  • Jha R; Katharine Dormandy Haemophilia and Thrombosis Centre, Royal Free London NHS Foundation Trust, London NW3 2QG, UK.
  • Brill SE; Katharine Dormandy Haemophilia and Thrombosis Centre, Royal Free London NHS Foundation Trust, London NW3 2QG, UK.
  • Bakhai A; Department of Anaesthesia, Birmingham Children's Hospital, Birmingham B4 6NH, UK.
  • Evans A; Department of Anaesthesia, Faculty of Medicine, Beni-Suef University Hospital, Beni-Suef University, Beni-Suef 2721562, Egypt.
  • Gilani F; NIHR Biomedical Research Centre Oxford, Oxford University Hospitals NHS Trust, University of Oxford, Oxford OX3 9DU, UK.
  • Gomez K; Bloomsbury Institute for Intensive Care Medicine, Department of Experimental and Translational Medicine, University College London, London WC1E 6JF, UK.
J Clin Med ; 12(18)2023 Sep 08.
Article em En | MEDLINE | ID: mdl-37762789

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials Idioma: En Revista: J Clin Med Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials Idioma: En Revista: J Clin Med Ano de publicação: 2023 Tipo de documento: Article