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Achiral Sm(III)-Based Metal-Organic Framework as a Luminescence Sensor for Enantiodiscrimination of Quinine and Quinidine.
Jia, Yuejiao; Cui, Linxia; Li, Dechao; Yang, Yefang; Qie, Shaowen; Su, Shuai; Hu, Ming; Gao, Rui.
Afiliação
  • Jia Y; Inner Mongolia Key Laboratory of Chemistry and Physics of Rare Earth Materials, College of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, China.
  • Cui L; Inner Mongolia Key Laboratory of Chemistry and Physics of Rare Earth Materials, College of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, China.
  • Li D; Inner Mongolia Key Laboratory of Chemistry and Physics of Rare Earth Materials, College of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, China.
  • Yang Y; Inner Mongolia Key Laboratory of Chemistry and Physics of Rare Earth Materials, College of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, China.
  • Qie S; Inner Mongolia Key Laboratory of Chemistry and Physics of Rare Earth Materials, College of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, China.
  • Su S; Inner Mongolia Key Laboratory of Chemistry and Physics of Rare Earth Materials, College of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, China.
  • Hu M; Inner Mongolia Key Laboratory of Chemistry and Physics of Rare Earth Materials, College of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, China.
  • Gao R; Inner Mongolia Key Laboratory of Chemistry and Physics of Rare Earth Materials, College of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, China.
Inorg Chem ; 62(40): 16288-16293, 2023 Oct 09.
Article em En | MEDLINE | ID: mdl-37767924
ABSTRACT
The effective discrimination and determination of the chiral antimalarial drugs quinine (QN) and quinidine (QD) are extremely important for human health. Herein, a 2D achiral Sm-based metal-organic framework (IMU-MOF1 = [Sm(tpba)(L)]n, where Htpba = 4-(2,2'6″,2'-terpyridin)-4'-ylbenzioc acid and H2L = 2,2'-biquinoline-4,4'-dicarboxylic acid) was successfully prepared by the solvothermal method. More importantly, IMU-MOF1 was designed as an ultrasensitive fluorescent probe for the identification of chiral enantiomer drugs. The limits of detection for QN and QD are 4.24 × 10-11 and 7.54 × 10-12 M, respectively. Furthermore, it was demonstrated that the stronger hydrogen-bonding interactions between IMU-MOF1 and quinine furnish a more efficient energy transfer to the ligands in the sensing process, resulting in a significant fluorescence enhancement of IMU-MOF1.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Inorg Chem Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Inorg Chem Ano de publicação: 2023 Tipo de documento: Article