Poly (ADP-Ribose) polymerase 1 and parthanatos in neurological diseases: From pathogenesis to therapeutic opportunities.

Xu, Xiaoxue; Sun, Bowen; Zhao, Chuansheng

Xu, Xiaoxue; Sun, Bowen; Zhao, Chuansheng.

Afiliação

Xu X; Department of Neurology, The First Affiliated Hospital of China Medical University, Shenyang, China; Key Laboratory of Neurological Disease Big Data of Liaoning Province, Shenyang, China. Electronic address: xiaoxue80cn@sina.com.
Sun B; Department of Neurology, The First Affiliated Hospital of China Medical University, Shenyang, China; Key Laboratory of Neurological Disease Big Data of Liaoning Province, Shenyang, China.
Zhao C; Department of Neurology, The First Affiliated Hospital of China Medical University, Shenyang, China; Key Laboratory of Neurological Disease Big Data of Liaoning Province, Shenyang, China. Electronic address: cszhao@cmu.edu.cn.

Neurobiol Dis ; 187: 106314, 2023 Oct 15.

Article em En | MEDLINE | ID: mdl-37783233

Assuntos

Transtorno do Espectro Autista; Doenças Neurodegenerativas; Parthanatos; Humanos; Poli(ADP-Ribose) Polimerase-1/metabolismo; Poli(ADP-Ribose) Polimerases/metabolismo; Ribose; Inibidores de Poli(ADP-Ribose) Polimerases; Epigênese Genética; Doenças Neurodegenerativas/patologia

Palavras-chave

PARP-1; PARP-1 inhibitors; cell death; neuroinflammation; oxidative stress; parthanatos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Neurodegenerativas / Transtorno do Espectro Autista / Parthanatos Tipo de estudo: Etiology_studies Limite: Humans Idioma: En Revista: Neurobiol Dis Ano de publicação: 2023 Tipo de documento: Article

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