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A comparison between field measurements of vapour concentrations of plant protection products and predictions by the BROWSE model.
Butler Ellis, M Clare; Felkers, Edgars; Adham, Sarah; Vinck, Anne-Kim; Bürling, Kathrin; Morgan, Neil.
Afiliação
  • Butler Ellis MC; Silsoe Spray Applications Unit Ltd, Building 42, Wrest Park, Silsoe, Bedford, MK45 4HP, UK. Electronic address: clare.butlerellis@ssau.co.uk.
  • Felkers E; Bayer AG, Crop Science Division, Monheim am Rhein, Germany.
  • Adham S; Corteva Agriscience, Abingdon, UK.
  • Vinck AK; Bayer SAS, Crop Science Division, Lyon, France.
  • Bürling K; Corteva Agriscience Germany GmbH, Munich, Germany.
  • Morgan N; Syngenta, Jealott's Hill International Research Centre, Bracknell, UK.
Regul Toxicol Pharmacol ; 145: 105504, 2023 Dec.
Article em En | MEDLINE | ID: mdl-37806614
ABSTRACT
A database of field measurements of air concentrations of pesticide active ingredients has previously been compiled by CropLife Europe with an aim to revise the default air concentration values and assumptions applied in assessing vapour exposure in the risk assessment of bystanders and residents. The BROWSE model, released in 2014, which is a regulatory risk assessment model that includes the exposure of residents and bystanders has a component relating to post-application vapour inhalation. Predictions of concentration deduced from exposures obtained using the BROWSE model were compared with field measurements of 24-h and 7-day average concentrations. The methodology for obtaining concentration estimates from the BROWSE model is described, and the criteria for including field studies in the comparison are given. The field data were adjusted to account for differences between the field experiment and the BROWSE scenario using factors derived from a separate plume dispersion model. This showed that BROWSE provides a satisfactory level of conservatism in determining potential exposures of residents and bystanders to vapour and could be a reliable alternative to replace the current EFSA approach for predicting vapour inhalation exposures for pesticides where no compound-specific data are available.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Praguicidas Tipo de estudo: Prognostic_studies / Risk_factors_studies País/Região como assunto: Europa Idioma: En Revista: Regul Toxicol Pharmacol Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Praguicidas Tipo de estudo: Prognostic_studies / Risk_factors_studies País/Região como assunto: Europa Idioma: En Revista: Regul Toxicol Pharmacol Ano de publicação: 2023 Tipo de documento: Article