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PRIMA-1 synergizes olaparib-induced cell death in p53 mutant triple negative human breast cancer cell line via restoring p53 function, arresting cell cycle, and inducing apoptosis.
Zaza, Mohamed; Rashed, Mohammed H; Elrefaey, Hesham; Hassan, Memy H; Abo-Salem, Osama M; El-Sayed, El-Sayed M.
Afiliação
  • Zaza M; Department of Pharmacology and Toxic1ology, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.
  • Rashed MH; Children's Cancer Hospital Egypt (CCHE 57357), Cairo, Egypt.
  • Elrefaey H; Department of Pharmacology and Toxic1ology, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.
  • Hassan MH; Department of Pharmacology and Toxic1ology, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.
  • Abo-Salem OM; Department of Pharmacology and Toxic1ology, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.
  • El-Sayed ESM; Department of Pharmacology and Toxic1ology, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.
Can J Physiol Pharmacol ; 102(1): 55-68, 2024 Jan 01.
Article em En | MEDLINE | ID: mdl-37818839
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Neoplasias de Mama Triplo Negativas Limite: Humans Idioma: En Revista: Can J Physiol Pharmacol Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Neoplasias de Mama Triplo Negativas Limite: Humans Idioma: En Revista: Can J Physiol Pharmacol Ano de publicação: 2024 Tipo de documento: Article