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Optimal control dynamics of Gonorrhea in a structured population.
Asamoah, Joshua Kiddy K; Safianu, Beilawu; Afrifa, Emmanuel; Obeng, Benjamin; Seidu, Baba; Wireko, Fredrick Asenso; Sun, Gui-Quan.
Afiliação
  • Asamoah JKK; School of Mathematics, North University of China, Taiyuan, Shanxi 030051, China.
  • Safianu B; Department of Mathematics, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
  • Afrifa E; Department of Mathematics, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
  • Obeng B; Department of Mathematics, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
  • Seidu B; Department of Mathematics, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
  • Wireko FA; Department of Mathematics, School of Mathematical Sciences, C. K. Tedam University of Technology and Applied Sciences, Navrongo, Ghana.
  • Sun GQ; Department of Mathematics, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Heliyon ; 9(10): e20531, 2023 Oct.
Article em En | MEDLINE | ID: mdl-37842629
ABSTRACT
Gonorrhea is a serious global health problem due to its high incidence, with approximately 82.4 million new cases in 2020. To evaluate the consequences of targeted dynamic control of gonorrhea infection transmission, a model for gonorrhea with optimal control analysis is proposed for a structured population. The study looked at the model's positively invariant and bounded regions. The gonorrhea secondary infection expression, R0 for the structured population is computed. The maximum principle of Pontryagin is utilised to construct the optimal system for the formulated mathematical model. To reduce the continuous propagation of gonorrhea, we incorporated education, condoms usage, vaccinations, and treatment as control strategies. The numerical simulations show that the number of infections decreases when the controls are implemented. The effectiveness of the controls is shown using the efficacy plots.
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 10_ODS3_salud_sexual_reprodutiva / 2_ODS3 Base de dados: MEDLINE Idioma: En Revista: Heliyon Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 10_ODS3_salud_sexual_reprodutiva / 2_ODS3 Base de dados: MEDLINE Idioma: En Revista: Heliyon Ano de publicação: 2023 Tipo de documento: Article