Regio-specific enzymatic glucosylation of triterpenoids from Antrodia camphorata and their biological activities.
Org Biomol Chem
; 21(42): 8467-8470, 2023 11 01.
Article
em En
| MEDLINE
| ID: mdl-37842833
ABSTRACT
The bacterial glycosyltransferase YjiC1 was used to glycosylate triterpenoids from the medicinal fungus Antrodia camphorata. Eleven new compounds were obtained from enzymatic reactions. Glucosylation could increase the inhibitory activities against COX-2, and improve the anti-inflammatory activities of Antrodia ergostanes on acute lung injury mice, especially (25R)-antcin C 7-O-ß-D-glucoside.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Triterpenos
/
Polyporales
/
Antrodia
Limite:
Animals
Idioma:
En
Revista:
Org Biomol Chem
Ano de publicação:
2023
Tipo de documento:
Article