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Overall survival following stereotactic radiosurgery for ten or more brain metastases: a systematic review and meta-analysis.
Rozati, Hamoun; Chen, Jiarong; Williams, Matt.
Afiliação
  • Rozati H; London Gamma Knife Centre, Platinum Medical Centre, Wellington Hospital, Lodge Road, London, UK.
  • Chen J; Computational Oncology Group, Department of Surgery and Cancer, Imperial College London, London, UK.
  • Williams M; Computational Oncology Group, Department of Surgery and Cancer, Imperial College London, London, UK.
BMC Cancer ; 23(1): 1004, 2023 Oct 19.
Article em En | MEDLINE | ID: mdl-37858075
This systematic review and meta-analysis is the first of its kind in the literature and provides information on overall survival outcomes and toxicities encountered in patients with ten or more brain metastases treated with stereotactic radiosurgery. Centres treating patients with ten or more brain metastases are doing so based only on retrospective real-world data analyses, the vast majority of which are from single centres and single radiotherapy platforms. This review provides an additional evidence resource for practitioners of stereotactic radiosurgery to aide in the management of this difficult patient group. The methods used to predict survival outcomes through the calculation of log hazard ratios and standard errors allowed analysis of small, retrospective case series. To our knowledge, this is the first meta-analysis of this patient group gives evidence for acceptable overall survival outcomes post-treatment, and provides further evidence for the use of stereotactic radiosurgery for these patients.Overall survival following stereotactic radiosurgery for ten or more brain metastases: a systematic review and meta-analysis.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Radiocirurgia Tipo de estudo: Systematic_reviews Limite: Humans Idioma: En Revista: BMC Cancer Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Radiocirurgia Tipo de estudo: Systematic_reviews Limite: Humans Idioma: En Revista: BMC Cancer Ano de publicação: 2023 Tipo de documento: Article