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Longitudinal nucleocapsid antibody testing reveals undocumented SARS-CoV-2 infections in patients with lung cancer.
Rodilla, Ananda M; Valanparambil, Rajesh M; Mack, Philip C; Hsu, Chih-Yuan; Cagan, Jazz; Tavolacci, Sooyun C; Carreño, Juan Manuel; Brody, Rachel; Moore, Amy; King, Jennifer C; Gomez, Jorge E; Rohs, Nicholas; Rolfo, Christian; Bunn, Paul A; Gerber, David E; Minna, John D; Krammer, Florian; Ramalingam, Suresh S; García-Sastre, Adolfo; Shyr, Yu; Ahmed, Rafi; Hirsch, Fred R.
Afiliação
  • Rodilla AM; Center for Thoracic Oncology, Tisch Cancer Institute and Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Valanparambil RM; Emory Vaccine Center, Emory University, Atlanta, GA, USA; Department of Microbiology and Immunology, Emory University, Atlanta, GA, USA.
  • Mack PC; Center for Thoracic Oncology, Tisch Cancer Institute and Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Hsu CY; Department of Biostatistics, Vanderbilt University, Nashville, TN, USA.
  • Cagan J; Center for Thoracic Oncology, Tisch Cancer Institute and Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Tavolacci SC; Center for Thoracic Oncology, Tisch Cancer Institute and Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Carreño JM; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Brody R; Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Moore A; LUNGevity Foundation, Bethesda, MD, USA.
  • King JC; GO(2) For Lung Cancer, Washington, DC, USA.
  • Gomez JE; Center for Thoracic Oncology, Tisch Cancer Institute and Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Rohs N; Center for Thoracic Oncology, Tisch Cancer Institute and Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Rolfo C; Center for Thoracic Oncology, Tisch Cancer Institute and Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Bunn PA; Division of Medical Oncology, University of Colorado Cancer Center, Aurora, CO, USA.
  • Gerber DE; Hamon Center for Therapeutic Oncology Research, Departments of Internal Medicine and Pharmacology UT Southwestern Medical Center, Dallas, TX, USA.
  • Minna JD; Hamon Center for Therapeutic Oncology Research, Departments of Internal Medicine and Pharmacology UT Southwestern Medical Center, Dallas, TX, USA.
  • Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medic
  • Ramalingam SS; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA.
  • García-Sastre A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount S
  • Shyr Y; Department of Biostatistics, Vanderbilt University, Nashville, TN, USA.
  • Ahmed R; Emory Vaccine Center, Emory University, Atlanta, GA, USA; Department of Microbiology and Immunology, Emory University, Atlanta, GA, USA.
  • Hirsch FR; Center for Thoracic Oncology, Tisch Cancer Institute and Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: fred.hirsch@mssm.edu.
Cancer Cell ; 41(11): 1838-1840, 2023 11 13.
Article em En | MEDLINE | ID: mdl-37863065
ABSTRACT
Patients diagnosed with lung cancer (LC) exhibit increased susceptibility to SARS-CoV-2 infection. Rodilla et al. monitor the levels of plasma anti-nucleocapsid antibodies within a cohort of fully vaccinated LC patients and reveal that the actual infection rate is nearly twice the documented rate, indicating a significant prevalence of unreported cases.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: COVID-19 / Neoplasias Pulmonares Limite: Humans Idioma: En Revista: Cancer Cell Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: COVID-19 / Neoplasias Pulmonares Limite: Humans Idioma: En Revista: Cancer Cell Ano de publicação: 2023 Tipo de documento: Article