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The mitochondrial fusion protein OPA1 is dispensable in the liver and its absence induces mitohormesis to protect liver from drug-induced injury.
Lee, Hakjoo; Lee, Tae Jin; Galloway, Chad A; Zhi, Wenbo; Xiao, Wei; de Mesy Bentley, Karen L; Sharma, Ashok; Teng, Yong; Sesaki, Hiromi; Yoon, Yisang.
Afiliação
  • Lee H; Department of Physiology, Medical College of Georgia, Augusta University, Augusta, GA, 30912, USA.
  • Lee TJ; Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta University, Augusta, GA, 30912, USA.
  • Galloway CA; Department of Pathology and Laboratory Medicine, and Center for Advanced Research Technologies, University of Rochester Medical Center, Rochester, NY, 14642, USA.
  • Zhi W; Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta University, Augusta, GA, 30912, USA.
  • Xiao W; Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta University, Augusta, GA, 30912, USA.
  • de Mesy Bentley KL; Department of Pathology and Laboratory Medicine, and Center for Advanced Research Technologies, University of Rochester Medical Center, Rochester, NY, 14642, USA.
  • Sharma A; Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta University, Augusta, GA, 30912, USA.
  • Teng Y; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
  • Sesaki H; Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
  • Yoon Y; Department of Physiology, Medical College of Georgia, Augusta University, Augusta, GA, 30912, USA. yyoon@augusta.edu.
Nat Commun ; 14(1): 6721, 2023 10 23.
Article em En | MEDLINE | ID: mdl-37872238
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Mitocondriais / Dinâmica Mitocondrial Limite: Animals Idioma: En Revista: Nat Commun Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Mitocondriais / Dinâmica Mitocondrial Limite: Animals Idioma: En Revista: Nat Commun Ano de publicação: 2023 Tipo de documento: Article