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Incorporation of CEUS and SWE parameters into a multivariate logistic regression model for the differential diagnosis of benign and malignant TI-RADS 4 thyroid nodules.
Li, Hong-Jing; Sui, Guo-Qing; Teng, Deng-Ke; Lin, Yuan-Qiang; Wang, Hui.
Afiliação
  • Li HJ; Department of Ultrasound, China-Japan Union Hospital of Ji Lin University, Changchun, Jilin, China.
  • Sui GQ; Department of Ultrasound, China-Japan Union Hospital of Ji Lin University, Changchun, Jilin, China.
  • Teng DK; Department of Ultrasound, China-Japan Union Hospital of Ji Lin University, Changchun, Jilin, China.
  • Lin YQ; Department of Ultrasound, China-Japan Union Hospital of Ji Lin University, Changchun, Jilin, China. linyuanqiang@jlu.edu.cn.
  • Wang H; Department of Ultrasound, China-Japan Union Hospital of Ji Lin University, Changchun, Jilin, China. whui66@jlu.edu.cn.
Endocrine ; 83(3): 691-699, 2024 Mar.
Article em En | MEDLINE | ID: mdl-37889469
ABSTRACT

PURPOSE:

To investigate the diagnostic value of contrast-enhanced ultrasound (CEUS) quantitative analysis parameters combined with shear wave elastography (SWE) quantitative parameters in the differentiation of benign and malignant ACR TI-RADS category 4 thyroid nodules and to provide a more effective reference for clinical work.

METHODS:

We analyzed 187 category 4 nodules, including 132 nodules in the development cohort and 55 nodules in the validation cohort, divided the development cohort into benign and malignant groups, and analyzed the differences in all CEUS and SWE quantitative parameters between the two groups. We selected the highest AUC of the two parameters, performed binary logistic regression analysis with the ACR TI-RADS score and constructed a diagnostic model. ROC curves were applied to evaluate their diagnostic efficacy.

RESULTS:

1) The diagnostic model had an AUC of 0.926, sensitivity of 87.5%, specificity of 86.8%, diagnostic threshold of 3, accuracy of 87.12%, positive predictive value of 86.15%, and negative predictive value of 88.06%. 2) The diagnostic model had an AUC of 0.890 in the validation cohort, sensitivity of 81.5%, specificity of 79.6%, and accuracy of 80.00%.

CONCLUSION:

The combined multiparameter construction of the nodule diagnostic model can effectively improve the diagnostic efficacy of 4 types of thyroid nodules and provide a new reference index for clinical diagnostic work.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nódulo da Glândula Tireoide / Técnicas de Imagem por Elasticidade Limite: Humans Idioma: En Revista: Endocrine Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nódulo da Glândula Tireoide / Técnicas de Imagem por Elasticidade Limite: Humans Idioma: En Revista: Endocrine Ano de publicação: 2024 Tipo de documento: Article