Factors influencing methotrexate pharmacokinetics highlight the need for individualized dose adjustment: a systematic review.

Yang, Yunyun; Liu, Zhengyue; Chen, Jingxia; Wang, Xuebin; Jiao, Zheng; Wang, Zhuo

Yang, Yunyun; Liu, Zhengyue; Chen, Jingxia; Wang, Xuebin; Jiao, Zheng; Wang, Zhuo.

Afiliação

Yang Y; Department of Pharmacy, Shanghai Changhai Hospital, the First Affiliated Hospital of Navy Medical University, 168 Changhai Rd, Shanghai, 200433, China.
Liu Z; Department of Pharmacy, Shanghai Changhai Hospital, the First Affiliated Hospital of Navy Medical University, 168 Changhai Rd, Shanghai, 200433, China.
Chen J; Department of Pharmacy, Shanghai Changhai Hospital, the First Affiliated Hospital of Navy Medical University, 168 Changhai Rd, Shanghai, 200433, China.
Wang X; Department of Pharmacy, Shanghai Changhai Hospital, the First Affiliated Hospital of Navy Medical University, 168 Changhai Rd, Shanghai, 200433, China.
Jiao Z; Department of Pharmacy, Shanghai Chest Hospital, Shanghai Jiao Tong University, 241 Huaihai West Road, Shanghai, 200030, China. jiaozheng@online.sh.cn.
Wang Z; Department of Pharmacy, Shanghai Changhai Hospital, the First Affiliated Hospital of Navy Medical University, 168 Changhai Rd, Shanghai, 200433, China. wangzhuo088@163.com.

Eur J Clin Pharmacol ; 80(1): 11-37, 2024 Jan.

Article em En | MEDLINE | ID: mdl-37934204

Assuntos

Antimetabólitos Antineoplásicos; Metotrexato; Adulto; Lactente; Recém-Nascido; Humanos; Criança

Palavras-chave

Apparent clearance; Methotrexate; Population pharmacokinetics; Volume of distribution

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Metotrexato / Antimetabólitos Antineoplásicos Tipo de estudo: Systematic_reviews Limite: Adult / Child / Humans / Infant / Newborn Idioma: En Revista: Eur J Clin Pharmacol Ano de publicação: 2024 Tipo de documento: Article

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