Subclinical Atherosclerosis Across the Menopausal Transition in Women With and Without HIV.
J Infect Dis
; 229(3): 780-785, 2024 Mar 14.
Article
em En
| MEDLINE
| ID: mdl-37947273
ABSTRACT
The menopausal transition is a pivotal time of cardiovascular risk, but knowledge is limited in HIV. We studied longitudinal carotid artery intima-media thickness (CIMT) in the Women's Interagency HIV Study (2004-2019; 979 women/3247 person-visits; 72% with HIV). Among women with HIV only, those who transitioned had greater age-related CIMT progression compared to those remaining premenopausal (difference in slope = 1.64â
µm/year, P = .002); and CIMT increased over time in the pretransition (3.47â
µm/year, P = .002) and during the menopausal transition (9.41â
µm/year, P < .0001), but not posttransition (2.9â
µm/year, P = .19). In women with HIV, menopause may accelerate subclinical atherosclerosis as measured by CIMT.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções por HIV
/
Aterosclerose
Limite:
Female
/
Humans
Idioma:
En
Revista:
J Infect Dis
Ano de publicação:
2024
Tipo de documento:
Article