Metabolomics reveals that chronic restraint stress alleviates carbon tetrachloride-induced hepatic fibrosis through the INSR/PI3K/AKT/AMPK pathway.

Zhang, Shanshan; Liu, Binjie; Huang, Lan; Zhang, Rong; An, Lin; Liu, Zhongqiu

Zhang, Shanshan; Liu, Binjie; Huang, Lan; Zhang, Rong; An, Lin; Liu, Zhongqiu.

Afiliação

Zhang S; Guangdong-Hong Kong-Macau Joint Lab On Chinese Medicine and Immune Disease Research, Guangdong Provincial Key Laboratory of Translational Cancer Research of Chinese Medicines, Joint International Research Laboratory of Translational Cancer Research of Chinese Medicines, International Institute for T
Liu B; Guangdong-Hong Kong-Macau Joint Lab On Chinese Medicine and Immune Disease Research, Guangdong Provincial Key Laboratory of Translational Cancer Research of Chinese Medicines, Joint International Research Laboratory of Translational Cancer Research of Chinese Medicines, International Institute for T
Huang L; Guangdong-Hong Kong-Macau Joint Lab On Chinese Medicine and Immune Disease Research, Guangdong Provincial Key Laboratory of Translational Cancer Research of Chinese Medicines, Joint International Research Laboratory of Translational Cancer Research of Chinese Medicines, International Institute for T
Zhang R; Guangdong-Hong Kong-Macau Joint Lab On Chinese Medicine and Immune Disease Research, Guangdong Provincial Key Laboratory of Translational Cancer Research of Chinese Medicines, Joint International Research Laboratory of Translational Cancer Research of Chinese Medicines, International Institute for T
An L; Guangdong-Hong Kong-Macau Joint Lab On Chinese Medicine and Immune Disease Research, Guangdong Provincial Key Laboratory of Translational Cancer Research of Chinese Medicines, Joint International Research Laboratory of Translational Cancer Research of Chinese Medicines, International Institute for T
Liu Z; Guangdong-Hong Kong-Macau Joint Lab On Chinese Medicine and Immune Disease Research, Guangdong Provincial Key Laboratory of Translational Cancer Research of Chinese Medicines, Joint International Research Laboratory of Translational Cancer Research of Chinese Medicines, International Institute for T

J Mol Med (Berl) ; 102(1): 113-128, 2024 Jan.

Article em En | MEDLINE | ID: mdl-37993562

Assuntos

Fosfatidilinositol 3-Quinases; Proteínas Proto-Oncogênicas c-akt; Camundongos; Animais; Proteínas Proto-Oncogênicas c-akt/metabolismo; Fosfatidilinositol 3-Quinases/metabolismo; Tetracloreto de Carbono/efeitos adversos; Tetracloreto de Carbono/metabolismo; Proteínas Quinases Ativadas por AMP/metabolismo; Betaína/farmacologia; Cirrose Hepática/metabolismo; Células Estreladas do Fígado/metabolismo

Palavras-chave

Carbon tetrachloride; Chronic restraint stress; Hepatic fibrosis; INSR pathway; Metabolomics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfatidilinositol 3-Quinases / Proteínas Proto-Oncogênicas c-akt Limite: Animals Idioma: En Revista: J Mol Med (Berl) Ano de publicação: 2024 Tipo de documento: Article

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