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Dexmedetomidine alleviates renal tubular ferroptosis in sepsis-associated AKI by KEAP1 regulating the degradation of GPX4.
Li, Jiarou; Liu, Yansong; Bai, Jingjing; Liu, Tiantian; Qin, Xionghai; Hu, Tianyou; Wang, Sicong; Li, Yunlong; Cui, Shanpeng; Quan, Zhen; Luo, Yiming; Zheng, Junbo; Wang, Hongliang.
Afiliação
  • Li J; Department of Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China; Future Medical Laboratory, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China.
  • Liu Y; Department of Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China; Future Medical Laboratory, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China.
  • Bai J; Department of Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China; Future Medical Laboratory, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China.
  • Liu T; Department of Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China; Future Medical Laboratory, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China.
  • Qin X; Future Medical Laboratory, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China; Department of Thoracic Surgery, Harbin Medical University Cancer Hospital, Harbin 150081, China.
  • Hu T; Department of Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China; Future Medical Laboratory, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China.
  • Wang S; Department of Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China.
  • Li Y; Department of Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China.
  • Cui S; Department of Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China; Future Medical Laboratory, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China.
  • Quan Z; Department of Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China; Future Medical Laboratory, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China.
  • Luo Y; Department of Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China; Future Medical Laboratory, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China.
  • Zheng J; Department of Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China. Electronic address: icuzhengjunbo@hrbmu.edu.cn.
  • Wang H; Department of Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China. Electronic address: icuwanghongliang@hrbmu.edu.cn.
Eur J Pharmacol ; 961: 176194, 2023 Dec 15.
Article em En | MEDLINE | ID: mdl-38000722
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 4_TD / 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Sepse / Dexmedetomidina / Injúria Renal Aguda / Ferroptose Limite: Animals / Humans / Male Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2023 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 4_TD / 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Sepse / Dexmedetomidina / Injúria Renal Aguda / Ferroptose Limite: Animals / Humans / Male Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2023 Tipo de documento: Article