Evaluation of the Anticancer and Biological Activities of Istaroxime via Ex Vivo Analyses, Molecular Docking and Conceptual Density Functional Theory Computations.

Gok, Ege; Unal, Naz; Gungor, Burcin; Karakus, Gulderen; Kaya, Savas; Canturk, Pakize; Katin, Konstantin P

Gok, Ege; Unal, Naz; Gungor, Burcin; Karakus, Gulderen; Kaya, Savas; Canturk, Pakize; Katin, Konstantin P.

Afiliação

Gok E; Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Sivas Cumhuriyet University, 58140 Sivas, Turkey.
Unal N; Department of Biochemistry, Faculty of Pharmacy, Yeditepe University, 34755 Istanbul, Turkey.
Gungor B; Department of Biochemistry, Faculty of Pharmacy, Yeditepe University, 34755 Istanbul, Turkey.
Karakus G; Department of Pharmaceutical Basic Sciences, Faculty of Pharmacy, Sivas Cumhuriyet University, 58140 Sivas, Turkey.
Kaya S; Department of Chemistry, Faculty of Science, Sivas Cumhuriyet University, 58140 Sivas, Turkey.
Canturk P; Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Sivas Cumhuriyet University, 58140 Sivas, Turkey.
Katin KP; Nanoengineering in Electronics, Spintronics and Photonics Institute, National Research Nuclear University MEPhI, 115409 Moscow, Russia.

Molecules ; 28(22)2023 Nov 07.

Article em En | MEDLINE | ID: mdl-38005181

Assuntos

Antineoplásicos; Etiocolanolona; Simulação de Acoplamento Molecular; Teoria da Densidade Funcional; Etiocolanolona/farmacologia; Antineoplásicos/farmacologia

Palavras-chave

Density Functional Theory; Istaroxime; anticancer drugs; topoisomerase enzymes

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Etiocolanolona / Antineoplásicos Idioma: En Revista: Molecules Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google