FastCAR: fast correction for ambient RNA to facilitate differential gene expression analysis in single-cell RNA-sequencing datasets.

Berg, Marijn; Petoukhov, Ilya; van den Ende, Inge; Meyer, Kerstin B; Guryev, Victor; Vonk, Judith M; Carpaij, Orestes; Banchero, Martin; Hendriks, Rudi W; van den Berge, Maarten; Nawijn, Martijn C

Berg, Marijn; Petoukhov, Ilya; van den Ende, Inge; Meyer, Kerstin B; Guryev, Victor; Vonk, Judith M; Carpaij, Orestes; Banchero, Martin; Hendriks, Rudi W; van den Berge, Maarten; Nawijn, Martijn C.

Afiliação

Berg M; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. m.berg@umcg.nl.
Petoukhov I; University of Groningen, University Medical Center Groningen, Groningen Research Institute, for Asthma and COPD (GRIAC), Groningen, The Netherlands. m.berg@umcg.nl.
van den Ende I; MIcompany, Amsterdam, The Netherlands.
Meyer KB; MIcompany, Amsterdam, The Netherlands.
Guryev V; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.
Vonk JM; University of Groningen, University Medical Center Groningen, Groningen Research Institute, for Asthma and COPD (GRIAC), Groningen, The Netherlands.
Carpaij O; European Research Institute for the Biology of Ageing (ERIBA), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Banchero M; University of Groningen, University Medical Center Groningen, Groningen Research Institute, for Asthma and COPD (GRIAC), Groningen, The Netherlands.
Hendriks RW; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
van den Berge M; University of Groningen, University Medical Center Groningen, Groningen Research Institute, for Asthma and COPD (GRIAC), Groningen, The Netherlands.
Nawijn MC; Department of Pulmonology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

BMC Genomics ; 24(1): 722, 2023 Nov 29.

Article em En | MEDLINE | ID: mdl-38030970

Assuntos

Perfilação da Expressão Gênica; RNA; Humanos; RNA/metabolismo; Perfilação da Expressão Gênica/métodos; Análise de Sequência de RNA/métodos; Transcriptoma; Projetos de Pesquisa; Análise de Célula Única/métodos

Palavras-chave

Ambient RNA correction; Decontamination; Single cell differential gene expression; sc-DGE; scRNA-seq

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Perfilação da Expressão Gênica Limite: Humans Idioma: En Revista: BMC Genomics Ano de publicação: 2023 Tipo de documento: Article

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