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The catalyst free synthesis of dibenzo[a,j]acridine and its applications in bioimaging of BF3 in HeLa cells.
Enbanathan, Saravanan; Iyer Sathiyanarayanan, Kulathu.
Afiliação
  • Enbanathan S; Department of Chemistry, School of Advanced Sciences and Vellore Institute of Technology, Vellore 632 014, India.
  • Iyer Sathiyanarayanan K; Department of Chemistry, School of Advanced Sciences and Vellore Institute of Technology, Vellore 632 014, India. Electronic address: sathiyanarayanank@vit.ac.in.
Methods ; 221: 65-72, 2024 01.
Article em En | MEDLINE | ID: mdl-38040205
ABSTRACT
In this paper, we discuss how tetrahydrodibenzo[a,j]acridine (4-HA) loses its hydrogen, which makes dibenzo[a,j]acridine (ARM) and also how 4-HA can be synthesized effectively using 2-tetralone in high yield. Dehydrogenative condensation and dehydrogenation are the two processes that make up the overall reaction of this synthetic approach. In addition, the presence of BF3 caused a remarkable fluorescence shift in ARM. Test paper analysis was used for examining the practical usefulness of ARM, which can be seen under UV light, resulting in this unique phenomenon. The fluorescent bio imaging experiment demonstrates that the sensor ARM has the capability to detect BF3 in living HeLa cells.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acridinas / Corantes Fluorescentes Limite: Humans Idioma: En Revista: Methods Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acridinas / Corantes Fluorescentes Limite: Humans Idioma: En Revista: Methods Ano de publicação: 2024 Tipo de documento: Article