The catalyst free synthesis of dibenzo[a,j]acridine and its applications in bioimaging of BF3 in HeLa cells.
Methods
; 221: 65-72, 2024 01.
Article
em En
| MEDLINE
| ID: mdl-38040205
ABSTRACT
In this paper, we discuss how tetrahydrodibenzo[a,j]acridine (4-HA) loses its hydrogen, which makes dibenzo[a,j]acridine (ARM) and also how 4-HA can be synthesized effectively using 2-tetralone in high yield. Dehydrogenative condensation and dehydrogenation are the two processes that make up the overall reaction of this synthetic approach. In addition, the presence of BF3 caused a remarkable fluorescence shift in ARM. Test paper analysis was used for examining the practical usefulness of ARM, which can be seen under UV light, resulting in this unique phenomenon. The fluorescent bio imaging experiment demonstrates that the sensor ARM has the capability to detect BF3 in living HeLa cells.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Acridinas
/
Corantes Fluorescentes
Limite:
Humans
Idioma:
En
Revista:
Methods
Ano de publicação:
2024
Tipo de documento:
Article