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A randomized double-blind clinical trial on safety and efficacy of tauroursodeoxycholic acid (TUDCA) as add-on treatment in patients affected by amyotrophic lateral sclerosis (ALS): the statistical analysis plan of TUDCA-ALS trial.
Lombardo, Flavia L; Spila Alegiani, Stefania; Mayer, Flavia; Cipriani, Marta; Lo Giudice, Maria; Ludolph, Albert Christian; McDermott, Christopher J; Corcia, Philippe; Van Damme, Philip; Van den Berg, Leonard H; Hardiman, Orla; Nicolini, Gabriele; Vanacore, Nicola; Dickie, Brian; Albanese, Alberto; Puopolo, Maria.
Afiliação
  • Lombardo FL; National Centre for Disease Prevention and Health Promotion, Italian National Institute of Health, Rome, Italy. flavia.lombardo@iss.it.
  • Spila Alegiani S; National Center for Drug Research and Evaluation, Italian National Institute of Health, Rome, Italy.
  • Mayer F; National Center for Drug Research and Evaluation, Italian National Institute of Health, Rome, Italy.
  • Cipriani M; Department of Statistical Sciences, Sapienza University of Rome, Rome, Italy.
  • Lo Giudice M; Department of Neuroscience, Italian National Institute of Health, Rome, Italy.
  • Ludolph AC; Neurology Department, IRCCS Humanitas Research Hospital, Rozzano, Italy.
  • McDermott CJ; Neurology Department, University of Ulm, Ulm, Germany.
  • Corcia P; German Centre of Neurodegenerative Diseases, Site Ulm, Ulm, Germany.
  • Van Damme P; Department of Neuroscience, Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, UK.
  • Van den Berg LH; Centre de Référence Maladie Rare (CRMR) SLA Et Les Autres Maladies du Neurone Moteur (FILSLAN), Tours, France.
  • Hardiman O; CHU Bretonneau, Tours, France.
  • Nicolini G; Federation des CRMR-SLA Tours-Limoges, LITORALS, Tours, France.
  • Vanacore N; Faculté de Médecine, INSERM U1253, "iBrain," Université François-Rabelais de Tours, Tours, France.
  • Dickie B; Neurology Department, University Hospitals Leuven, Louvain, Belgium.
  • Albanese A; Neuroscience Department, KU Leuven, Louvain, Belgium.
  • Puopolo M; Department of Neurology, UMC Utrecht Brain Center, University Medical Centre Utrecht, Utrecht, Netherlands.
Trials ; 24(1): 792, 2023 Dec 05.
Article em En | MEDLINE | ID: mdl-38053196
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fármacos Neuroprotetores / Esclerose Lateral Amiotrófica Limite: Humans Idioma: En Revista: Trials Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fármacos Neuroprotetores / Esclerose Lateral Amiotrófica Limite: Humans Idioma: En Revista: Trials Ano de publicação: 2023 Tipo de documento: Article