Your browser doesn't support javascript.
loading
The clinical impacts of the prognostic nutritional index for the esophageal cancer patients who received curative treatment.
Aoyama, Toru; Atsumi, Yosuke; Kawahara, Shinnosuke; Tamagawa, Hiroshi; Tamagawa, Ayako; Maezawa, Yukio; Kano, Kazuki; Murakawa, Masaaki; Kazama, Keisuke; Numata, Masakatsu; Oshima, Takashi; Yukawa, Norio; Masuda, Munetaka; Rino, Yasushi.
Afiliação
  • Aoyama T; Department of Surgery, Yokohama City University, Yokohama, Japan.
  • Atsumi Y; Department of Surgery, Yokohama City University, Yokohama, Japan.
  • Kawahara S; Department of Surgery, Yokohama City University, Yokohama, Japan.
  • Tamagawa H; Department of Surgery, Yokohama City University, Yokohama, Japan.
  • Tamagawa A; Department of Surgery, Yokohama City University, Yokohama, Japan.
  • Maezawa Y; Department of Surgery, Yokohama City University, Yokohama, Japan.
  • Kano K; Department of Surgery, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospital, Tokyo, Japan.
  • Murakawa M; Department of Surgery, Yokohama City University, Yokohama, Japan.
  • Kazama K; Department of Surgery, Yokohama City University, Yokohama, Japan.
  • Numata M; Department of Surgery, Yokohama City University, Yokohama, Japan.
  • Oshima T; Department of Surgery, Yokohama City University, Yokohama, Japan.
  • Yukawa N; Department of Surgery, Yokohama City University, Yokohama, Japan.
  • Masuda M; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
  • Rino Y; Department of Surgery, Yokohama City University, Yokohama, Japan.
J Cancer Res Ther ; 20(3): 898-903, 2024 Apr 01.
Article em En | MEDLINE | ID: mdl-38102916
ABSTRACT

BACKGROUND:

We investigated the impact of the prognostic nutritional index (PNI) on esophageal cancer survival and recurrence after curative treatment.

METHODS:

This study included 120 patients who underwent curative surgery followed by the adjuvant treatment for esophageal cancer between 2008 and 2018. The risk factors for overall survival (OS) and recurrence-free survival (RFS) were identified.

RESULTS:

The PNI of 49 was regarded to be the optimal critical point of classification considering the 1-year, 3-year, and 5-year survival rate. The OS rates at three and five years after surgery were 47.4% and 36.0% in the PNI low group, respectively, and 62.5% and 56.5% in the PNI high group, which amounted to a statistically significant difference ( P = 0.020). The RFS rates at three and five years after surgery were 31.0% and 24.8% in the PNI low group, respectively, and 50.9% and 42.8% in the PNI high group, which amounted to a statistically significant difference ( P = 0.020). A multivariate analysis demonstrated that the PNI was a significant independent risk factor for the OS and a marginally significant independent risk factor forRFS.

CONCLUSION:

The PNI was a risk factor for survival in patients who underwent curative treatment for esophageal cancer. It is necessary to develop the effective plan of the perioperative care and the surgical strategy according to the PNI.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Avaliação Nutricional Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Cancer Res Ther Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Avaliação Nutricional Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Cancer Res Ther Ano de publicação: 2024 Tipo de documento: Article