Characteristics of vitiligo patients with versus without associated autoimmune thyroid disease.

ABSTRACT

BACKGROUND: Clinical data are limited in patients with vitiligo with or without autoimmune thyroid disease. OBJECTIVES: The objective of the study was to investigate the clinical features and basic data of patients with vitiligo, especially those with autoimmune thyroid disease. METHODS: The study was a single-center retrospective study. A total of 1305 patients with vitiligo from June 2018 to May 2023 were included, and the clinical characteristics and basic information of the patients were recorded in detail. RESULTS: We identified an association between sex (odds ratio [OR] 2.380; 95% confidence interval [CI] 1.772-1.198), vitiligo duration (OR 1.449; 95% CI 1.076-1.952), skin involvement exceeding 5% of the body surface area (OR 3.764; 95% CI 2.134-6.640), negative emotions (OR 3.076; 95% CI 2.292-4.127), vitiligo type (OR 1.974; 95% CI 1.096-3.555), family history of AITD (OR 4.979; 95% CI 2.687-9.225), and family history of AD (OR 2.418; 95% CI 1.410-4.146) and patients with vitiligo. CONCLUSIONS: For patients with statistically significant associated risk factors, differential diagnosis and early intervention should be performed.