In-field detection and characterization of B/Victoria lineage deletion variant viruses causing early influenza activity and an outbreak in Louisiana, 2019.
Influenza Other Respir Viruses
; 18(1): e13246, 2024 Jan.
Article
em En
| MEDLINE
| ID: mdl-38188372
ABSTRACT
Background:
In 2019, the Louisiana Department of Health reported an early influenza B/Victoria (B/VIC) virus outbreak.Method:
As it was an atypically large outbreak, we deployed to Louisiana to investigate it using genomics and a triplex real-time RT-PCR assay to detect three antigenically distinct B/VIC lineage variant viruses.Results:
The investigation indicated that B/VIC V1A.3 subclade, containing a three amino acid deletion in the hemagglutinin and known to be antigenically distinct to the B/Colorado/06/2017 vaccine virus, was the most prevalent circulating virus within the specimens evaluated (86/88 in real-time RT-PCR).Conclusion:
This work underscores the value of portable platforms for rapid, onsite pathogen characterization.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
1_ASSA2030
Base de dados:
MEDLINE
Assunto principal:
Vacinas contra Influenza
/
Influenza Humana
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
País/Região como assunto:
America do norte
Idioma:
En
Revista:
Influenza Other Respir Viruses
Ano de publicação:
2024
Tipo de documento:
Article