Membrane Dynamics and Cation Handling in Ferroptosis.
Physiology (Bethesda)
; 39(2): 73-87, 2024 Mar 01.
Article
em En
| MEDLINE
| ID: mdl-38193763
ABSTRACT
Ferroptosis, a regulated cell death hallmarked by excessive lipid peroxidation, is implicated in various (patho)physiological contexts. During ferroptosis, lipid peroxidation leads to a diverse change in membrane properties and the dysregulation of ion homeostasis via the cation channels, ultimately resulting in plasma membrane rupture. This review illuminates cellular membrane dynamics and cation handling in ferroptosis regulation.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ferroptose
Limite:
Humans
Idioma:
En
Revista:
Physiology (Bethesda)
Ano de publicação:
2024
Tipo de documento:
Article