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The importance of animal specificity in animal experimentation, part I: Anatomy in relation to pediatric urology.
Fossum, Magdalena; Kaefer, Martin; Bagli, Darius; Harper, Luke; Herbst, Katherine W; Nelson, Caleb P; Braga, Luis H; Nieuwhof-Leppink, Anka; Kalfa, Nicolas; Garriboli, Massimo; Cascio, Salvatore.
Afiliação
  • Fossum M; Department of Pediatric Surgery, Center of Cancer and Organ Diseases, Rigshospitalet, Copenhagen University, Copenhagen, Denmark; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden. Electronic address: maria.magdalena.fossum@regionh.dk.
  • Kaefer M; Riley Hospital for Children, Indiana University, Indianapolis, IN, United States.
  • Bagli D; Division of Urology, Departments of Surgery and Physiology, University of Toronto, Developmental and Stem Cell Biology, The Hospital for Sick Children and Research Institute, Toronto, Ontario, Canada.
  • Harper L; Service de Chirurgie Pédiatrique, Hôpital Pellegrin-Enfants, CHU de Bordeaux, France.
  • Herbst KW; Division of Urology, Research Institute, Connecticut Children's Medical Center, Hartford, CT, United States.
  • Nelson CP; Department of Urology, Boston Children's Hospital and Harvard Medical School, MA, United States.
  • Braga LH; Department of Surgery, Division of Urology, McMaster University, McMaster Children's Hospital, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada.
  • Nieuwhof-Leppink A; Department Urotherapy, Wilhelmina Children's Hospital, Part of University Medical Center Utrecht, Netherlands.
  • Kalfa N; Department of Pediatric Surgery and Urology, Lapeyronie Hospital, CHU Montpellier, France; UMR1302 Institute Desbrest of Epidemiology and Public Health, INSERM, University Montpellier, Montpellier, France.
  • Garriboli M; Department of Paediatric Urology, Evelina London Children's Hospital, Westminster Bridge Road, London, SE1 7EH, United Kingdom.
  • Cascio S; Department of Pediatric Surgery, School of Medicine, University College Dublin and Children's Health Ireland at Temple Street, Dublin, Ireland.
J Pediatr Urol ; 20(2): 312-314, 2024 Apr.
Article em En | MEDLINE | ID: mdl-38199905
ABSTRACT
Why and when is animal experimentation relevant? The answer to this question depends on the research question. In this short educational article we aim to raise awareness of the importance of formulating a very specific research question before choosing an animal species. An awareness of anatomical and physiological differences vis-a-vis similarities between species, will increase the potential for obtaining data that is relevant for translation to human conditions.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Urologia / Experimentação Animal Limite: Animals / Child / Humans Idioma: En Revista: J Pediatr Urol Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Urologia / Experimentação Animal Limite: Animals / Child / Humans Idioma: En Revista: J Pediatr Urol Ano de publicação: 2024 Tipo de documento: Article