Biomarkers of the relationship of particulate matter exposure with the progression of chronic respiratory diseases.
Korean J Intern Med
; 39(1): 25-33, 2024 01.
Article
em En
| MEDLINE
| ID: mdl-38225823
ABSTRACT
A high level of particulate matter (PM) in air is correlated with the onset and development of chronic respiratory diseases. We conducted a systematic literature review, searching the MEDLINE, EMBASE, and Cochrane databases for studies of biomarkers of the effect of PM exposure on chronic respiratory diseases and the progression thereof. Thirty-eight articles on biomarkers of the progression of chronic respiratory diseases after exposure to PM were identified, four of which were eligible for review. Serum, sputum, urine, and exhaled breath condensate biomarkers of the effect of PM exposure on chronic obstructive pulmonary disease (COPD) and asthma had a variety of underlying mechanisms. We summarized the functions of biomarkers linked to COPD and asthma and their biological plausibility. We identified few biomarkers of PM exposure-related progression of chronic respiratory diseases. The included studies were restricted to those on biomarkers of the relationship of PM exposure with the progression of chronic respiratory diseases. The predictive power of biomarkers of the effect of PM exposure on chronic respiratory diseases varies according to the functions of the biomarkers.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
2_ODS3
Base de dados:
MEDLINE
Assunto principal:
Asma
/
Doença Pulmonar Obstrutiva Crônica
/
Poluentes Atmosféricos
/
Poluição do Ar
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
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Prognostic_studies
/
Systematic_reviews
Limite:
Humans
Idioma:
En
Revista:
Korean J Intern Med
Ano de publicação:
2024
Tipo de documento:
Article