Efficacy and safety of brexucabtagene autoleucel CAR T-cell therapy with BTK inhibitors in the treatment of relapsed mantle cell lymphoma with central nervous system involvement.

Lionel, Anath C; Gurumurthi, Ashwath; Fetooh, Ahmed; Eldaya, Rami; Ahmed, Sairah; Iyer, Swaminathan P; Nastoupil, Loretta J; Westin, Jason; Nair, Ranjit; Fayad, Luis; Malpica, Luis; Tummala, Sudhakar; Flowers, Christopher; Neelapu, Sattva S; Wang, Michael L; Jain, Preetesh

Lionel, Anath C; Gurumurthi, Ashwath; Fetooh, Ahmed; Eldaya, Rami; Ahmed, Sairah; Iyer, Swaminathan P; Nastoupil, Loretta J; Westin, Jason; Nair, Ranjit; Fayad, Luis; Malpica, Luis; Tummala, Sudhakar; Flowers, Christopher; Neelapu, Sattva S; Wang, Michael L; Jain, Preetesh.

Afiliação

Lionel AC; Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Gurumurthi A; Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Fetooh A; Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Eldaya R; Department of Neuroradiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Ahmed S; Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Iyer SP; Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Nastoupil LJ; Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Westin J; Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Nair R; Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Fayad L; Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Malpica L; Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Tummala S; Department of Neuro-oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Flowers C; Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Neelapu SS; Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Wang ML; Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Jain P; Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Leuk Lymphoma ; 65(5): 669-673, 2024 May.

Article em En | MEDLINE | ID: mdl-38248629

Assuntos

Tirosina Quinase da Agamaglobulinemia; Neoplasias do Sistema Nervoso Central; Imunoterapia Adotiva; Linfoma de Célula do Manto; Inibidores de Proteínas Quinases; Humanos; Imunoterapia Adotiva/métodos; Imunoterapia Adotiva/efeitos adversos; Linfoma de Célula do Manto/tratamento farmacológico; Linfoma de Célula do Manto/terapia; Linfoma de Célula do Manto/patologia; Tirosina Quinase da Agamaglobulinemia/antagonistas & inibidores; Neoplasias do Sistema Nervoso Central/terapia; Neoplasias do Sistema Nervoso Central/tratamento farmacológico; Inibidores de Proteínas Quinases/uso terapêutico; Inibidores de Proteínas Quinases/efeitos adversos; Resultado do Tratamento; Masculino; Pessoa de Meia-Idade; Recidiva Local de Neoplasia/tratamento farmacológico; Idoso; Receptores de Antígenos Quiméricos; Feminino; Terapia Combinada

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoterapia Adotiva / Neoplasias do Sistema Nervoso Central / Linfoma de Célula do Manto / Inibidores de Proteínas Quinases / Tirosina Quinase da Agamaglobulinemia Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Leuk Lymphoma Ano de publicação: 2024 Tipo de documento: Article

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