Immunity as biophysics at the surface of a T cell.
Immunity
; 57(2): 193-195, 2024 Feb 13.
Article
em En
| MEDLINE
| ID: mdl-38354696
ABSTRACT
Different antibodies can bind to the same targets on the surface of immune cells with opposite biologic effects. These effects-agonism, antagonism, or partial agonism-are so poorly understood that drug developers must screen antibodies for relevant desired characteristics. In this issue of Immunity, Lippert et al. define molecular mechanisms that dictate antibody behavior, ushering in an era of directed antibody design.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Linfócitos T
/
Anticorpos
Idioma:
En
Revista:
Immunity
Ano de publicação:
2024
Tipo de documento:
Article