Neutrophil elastase-dependent cleavage of LTA4H alters its aminopeptidase activity in cystic fibrosis.

Xu, Xin; Li, Jin-Dong; Green, Todd J; Wilson, Landon; Genschmer, Kristopher; Russell, Derek; Blalock, J Edwin; Gaggar, Amit

Xu, Xin; Li, Jin-Dong; Green, Todd J; Wilson, Landon; Genschmer, Kristopher; Russell, Derek; Blalock, J Edwin; Gaggar, Amit.

Afiliação

Xu X; Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Li JD; Program in Protease and Matrix Biology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Green TJ; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, USA.
Wilson L; Lung Health Center and Program in Pulmonary Biology, University of Alabama at Birmingham, Birmingham, AL, USA.
Genschmer K; Medical Service at Birmingham VA Medical Center, Birmingham, AL, USA.
Russell D; Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Blalock JE; Program in Protease and Matrix Biology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Gaggar A; Lung Health Center and Program in Pulmonary Biology, University of Alabama at Birmingham, Birmingham, AL, USA.

Eur Respir J ; 63(3)2024 Mar.

Article em En | MEDLINE | ID: mdl-38387968

Assuntos

Fibrose Cística; Elastase de Leucócito; Humanos; Proteólise; Aminopeptidases/genética; Neutrófilos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Elastase de Leucócito / Fibrose Cística Limite: Humans Idioma: En Revista: Eur Respir J Ano de publicação: 2024 Tipo de documento: Article

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