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Many faces, many places: delving deeper into CAF heterogeneity in NSCLC.
Papavassiliou, Kostas A; Adamopoulos, Christos; Papavassiliou, Athanasios G.
Afiliação
  • Papavassiliou KA; First University Department of Respiratory Medicine, 'Sotiria' Hospital, Medical School, National and Kapodistrian University of Athens, Athens 11527, Greece.
  • Adamopoulos C; Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, Athens 11527, Greece; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Papavassiliou AG; Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, Athens 11527, Greece. Electronic address: papavas@med.uoa.gr.
Trends Cancer ; 10(4): 277-279, 2024 Apr.
Article em En | MEDLINE | ID: mdl-38395732
ABSTRACT
In a recent study published in Cancer Cell, Cords et al. employed multiplexed imaging mass cytometry to analyze cancer-associated fibroblast (CAF) heterogeneity in 1070 NSCLC patients. This work defined good and poor prognostic CAF phenotypes, the latter associated with metastasis and chemoresistance, as well as revealed that CAF spatial location correlates with immune cell infiltration and clinical outcome.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Fibroblastos Associados a Câncer / Neoplasias Pulmonares Limite: Humans Idioma: En Revista: Trends Cancer Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Fibroblastos Associados a Câncer / Neoplasias Pulmonares Limite: Humans Idioma: En Revista: Trends Cancer Ano de publicação: 2024 Tipo de documento: Article