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Formulation and evaluation of antioxidant and antibacterial activity of a peel-off facial masks moisturizer containing curcumin and Rosa Damascena extract.
Nemati, Mohammad Mehdi; Abedi, Mehdi; Ghasemi, Younes; Ashrafi, Hajar; Haghdel, Mobin.
Afiliação
  • Nemati MM; Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Abedi M; Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Ghasemi Y; Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Ashrafi H; Department of Pharmaceutical Biotechnology, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Haghdel M; Department of Pharmaceutics, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
J Cosmet Dermatol ; 23(6): 2156-2169, 2024 Jun.
Article em En | MEDLINE | ID: mdl-38406887
ABSTRACT

BACKGROUND:

Acne is a common skin issue that typically occurs during adolescence. It causes long-lasting redness and swelling in the skin. An alternative approach to treating acne could involve using a cosmetic facial mask containing herbal ingredients such as Curcumin and Rosa Damascena extract for its antibacterial properties.

AIMS:

This study aims to create and try out a peel-off mask gel made from Curcumin and R. Damascena extract. This gel is intended to have the ability to kill bacteria such as Staphylococcus aureus, Escherichia coli, and Propionibacterium acnes and remove dead cells from the skin surface.

METHODS:

The peel-off mask was made using polyvinyl alcohol (PVA) in 8% and 10% as solidifier. The evaluation of peel-off masks comprises the examination of physiochemical and mechanical aspects. Furthermore, their longevity, effectiveness, and antibacterial properties are also considered.

RESULTS:

The white color, pleasant smell, and soft texture were the defining features of the peel-off gel mask. The changes in PVA affect the pH level, thickness, and how quickly the peel-off mask dries. The stability test found that the peel-off mask had no significant physical changes when exposed to freezing and thawing. However, there were some differences in color and separation when using the real-time method. A prepared peel-off mask containing 10% PVA and curcumin works best against P. acne. The amount of PVA in the formula affected the physical and chemical qualities, but it did not impact on the antibacterial abilities of the peel-off mask gel. The best formula that gives the best results uses 10% PVA + curcumin.

CONCLUSIONS:

Using the Curcumin and R. Damascena extract in the creation of the peel-off mask gel ensures its efficacy and safety for skin application.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Staphylococcus aureus / Extratos Vegetais / Acne Vulgar / Curcumina / Rosa / Antibacterianos / Antioxidantes Limite: Humans Idioma: En Revista: J Cosmet Dermatol Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Staphylococcus aureus / Extratos Vegetais / Acne Vulgar / Curcumina / Rosa / Antibacterianos / Antioxidantes Limite: Humans Idioma: En Revista: J Cosmet Dermatol Ano de publicação: 2024 Tipo de documento: Article