Antipsychotics in Alzheimer's Disease: Current Status and Therapeutic Alternatives.
Curr Alzheimer Res
; 20(10): 682-691, 2023.
Article
em En
| MEDLINE
| ID: mdl-38409713
ABSTRACT
Psychosis and hyperactive behaviors, such as agitation and wandering, affect a significant proportion of patients with Alzheimer's disease (AD). These symptoms are often treated with antipsychotics, usually in an off-label approach. This mini-review provides an updated perspective on the pharmacological approach for the neuropsychiatric symptoms (NPS) in AD. The results of new studies have provided a better understanding of AD-related NPS management, but high-quality evidence still needs to be obtained. Herein, we argue for a more cautious approach to the use of antipsychotics in AD and highlight the importance of exploring alternative treatments for NPS. By doing so, we can ensure that patients with AD receive optimal care that is both effective and safe.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtornos Psicóticos
/
Antipsicóticos
/
Doença de Alzheimer
Limite:
Humans
Idioma:
En
Revista:
Curr Alzheimer Res
Ano de publicação:
2023
Tipo de documento:
Article